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1.
J Am Geriatr Soc ; 69(6): 1422-1428, 2021 06.
Article in English | MEDLINE | ID: covidwho-1211533

ABSTRACT

Geriatricians have long debated the parameters, positioning, and prospects of their specialty. The year 2020 started full of promise as many organizations anticipated assessing themselves using perfect, or 2020, vision. While challenging on several levels, the momentous combination of events in 2020-the COVID-19 pandemic, Racial Justice Movement, and the November elections-provided Geriatric Medicine several opportunities to firmly secure a position in the mainstream. As we reflect on the new perspectives, programs, and partnerships initiated in 2020, five broader lessons emerge that can help safeguard the future of Geriatrics: the field could employ more intentional "direct to consumer" marketing strategies, expand the scope of what it means to be a patient advocate, pursue new strategic partnerships, take the opportunity to address racial injustice, and leverage existing skillsets to expand scope of care for patients. Given the interdisciplinary nature of Geriatrics, it is fitting that many of these lessons build upon this collaborative philosophy and are derived from domains outside of health care. So in an unexpected way, the events of 2020 may actually help Geriatrics see, with 2020 vision, how to remain mainstream. With this new clarity, Geriatrics holds renewed promise to truly become specialists in whole-person care and it is our hope that, with insight from the lessons shared here, the specialty brings this vision to fruition in the current decade and beyond.


Subject(s)
COVID-19 , Geriatrics , Health Services Needs and Demand , Aged , Geriatrics/standards , Geriatrics/trends , Health Services Needs and Demand/standards , Health Services Needs and Demand/trends , Humans , SARS-CoV-2
2.
J Transl Med ; 18(1): 390, 2020 10 15.
Article in English | MEDLINE | ID: covidwho-863645

ABSTRACT

While the COVID-19 pandemic has spurred intense research and collaborative discovery worldwide, the development of a safe, effective, and targeted antiviral from the ground up is time intensive. Therefore, most antiviral discovery efforts are focused on the re-purposing of clinical stage or approved drugs. While emerging data on drugs undergoing COVID-19 repurpose are intriguing, there is an undeniable need to develop broad-spectrum antivirals to prevent future viral pandemics of unknown origin. The ideal drug to curtail rapid viral spread would be a broad-acting agent with activity against a wide range of viruses. Such a drug would work by modulating host-proteins that are often shared by multiple virus families thereby enabling preemptive drug development and therefore rapid deployment at the onset of an outbreak. Targeting host-pathways and cellular proteins that are hijacked by viruses can potentially offer broad-spectrum targets for the development of future antiviral drugs. Such host-directed antivirals are also likely to offer a higher barrier to the development and selection of drug resistant mutations. Given that most approved antivirals do not target host-proteins, we reinforce the need for the development of such antivirals that can be used in pre- and post-exposure populations.


Subject(s)
Antiviral Agents , Betacoronavirus/drug effects , Coronavirus Infections/drug therapy , Drug Discovery , Health Services Needs and Demand , Host-Pathogen Interactions/drug effects , Pneumonia, Viral/drug therapy , Anti-Inflammatory Agents/pharmacology , Anti-Inflammatory Agents/therapeutic use , Antiviral Agents/classification , Antiviral Agents/pharmacology , Antiviral Agents/therapeutic use , Betacoronavirus/genetics , COVID-19 , Coronavirus Infections/epidemiology , Coronavirus Infections/virology , Drug Delivery Systems/methods , Drug Delivery Systems/standards , Drug Discovery/organization & administration , Drug Discovery/standards , Drug Discovery/trends , Global Health , Health Services Needs and Demand/organization & administration , Health Services Needs and Demand/standards , Health Services Needs and Demand/trends , Humans , Mutagenesis/drug effects , Needs Assessment/organization & administration , Needs Assessment/standards , Pandemics , Pneumonia, Viral/epidemiology , Pneumonia, Viral/virology , SARS-CoV-2 , Virus Internalization/drug effects
4.
Anesth Analg ; 131(2): 403-409, 2020 08.
Article in English | MEDLINE | ID: covidwho-663546
5.
Phlebology ; 35(8): 550-555, 2020 Sep.
Article in English | MEDLINE | ID: covidwho-660290

ABSTRACT

The coronavirus disease 2019 (COVID-19) global pandemic has resulted in diversion of healthcare resources to the management of patients infected with SARS-CoV-2 virus. Elective interventions and surgical procedures in most countries have been postponed and operating room resources have been diverted to manage the pandemic. The Venous and Lymphatic Triage and Acuity Scale was developed to provide an international standard to rationalise and harmonise the management of patients with venous and lymphatic disorders or vascular anomalies. Triage urgency was determined based on clinical assessment of urgency with which a patient would require medical treatment or surgical intervention. Clinical conditions were classified into six categories of: (1) venous thromboembolism (VTE), (2) chronic venous disease, (3) vascular anomalies, (4) venous trauma, (5) venous compression and (6) lymphatic disease. Triage urgency was categorised into four groups and individual conditions were allocated to each class of triage. These included (1) medical emergencies (requiring immediate attendance), example massive pulmonary embolism; (2) urgent (to be seen as soon as possible), example deep vein thrombosis; (3) semi-urgent (to be attended to within 30-90 days), example highly symptomatic chronic venous disease, and (4) discretionary/non-urgent- (to be seen within 6-12 months), example chronic lymphoedema. Venous and Lymphatic Triage and Acuity Scale aims to standardise the triage of patients with venous and lymphatic disease or vascular anomalies by providing an international consensus-based classification of clinical categories and triage urgency. The scale may be used during pandemics such as the current COVID-19 crisis but may also be used as a general framework to classify urgency of the listed conditions.


Subject(s)
Coronavirus Infections/therapy , Decision Support Systems, Clinical/standards , Decision Support Techniques , Emergency Service, Hospital/standards , Lymphatic Diseases/therapy , Pneumonia, Viral/therapy , Triage/standards , Vascular Diseases/therapy , COVID-19 , Clinical Decision-Making , Consensus , Coronavirus Infections/diagnosis , Coronavirus Infections/epidemiology , Coronavirus Infections/transmission , Health Services Needs and Demand/standards , Humans , Lymphatic Diseases/diagnosis , Lymphatic Diseases/epidemiology , Pandemics , Patient Selection , Pneumonia, Viral/diagnosis , Pneumonia, Viral/epidemiology , Pneumonia, Viral/transmission , Vascular Diseases/diagnosis , Vascular Diseases/epidemiology
6.
Nat Med ; 26(7): 1005-1008, 2020 07.
Article in English | MEDLINE | ID: covidwho-595980
7.
Diabetes Metab Syndr ; 14(5): 797-799, 2020.
Article in English | MEDLINE | ID: covidwho-595346

ABSTRACT

BACKGROUND AND AIMS: With restrictions on face to face clinical consultations in the COVID-19 pandemic, Telemedicine has become an essential tool in providing continuity of care to patients. We explore the common pitfalls in remote consultations and strategies that can be adopted to avoid them. METHODS: We have done a comprehensive review of the literature using suitable keywords on the search engines of PubMed, SCOPUS, Google Scholar and Research Gate in the first week of May 2020 including 'COVID-19', 'telemedicine' and 'remote consultations'. RESULTS: Telemedicine has become an integral part to support patient's clinical care in the current COVID-19 pandemic now and will be in the future for both primary and secondary care. Common pitfalls can be identified and steps can be taken to prevent them. CONCLUSION: Telemedicine it is going to play a key role in future of health medicine, however, telemedicine technology should be applied in appropriate settings and situations. Suitable training, enhanced documentations, communication and observing information governance guidelines will go a long way in avoiding pitfalls associated with remote consultations.


Subject(s)
Coronavirus Infections/epidemiology , Health Services Needs and Demand , Patient Acceptance of Health Care , Pneumonia, Viral/epidemiology , Referral and Consultation/organization & administration , Telemedicine/organization & administration , Betacoronavirus/physiology , COVID-19 , Health Services Needs and Demand/organization & administration , Health Services Needs and Demand/standards , Humans , Pandemics , Patient Acceptance of Health Care/statistics & numerical data , Quarantine/organization & administration , Quarantine/standards , Referral and Consultation/standards , Referral and Consultation/trends , SARS-CoV-2 , Telemedicine/methods , Telemedicine/standards , Telemedicine/trends
9.
Braz Oral Res ; 34: e047, 2020.
Article in English | MEDLINE | ID: covidwho-263241

ABSTRACT

The emergence of severe acute respiratory coronavirus 2 (SARS-CoV-2) and its association with severe pneumonia and deaths has exposed gaps in the health systems of several countries worldwide. Although the necessary focus has been to care for hospitalized patients, the strengthening of Primary Health Care (PHC) actions is necessary. PHC is the gateway to the health system in several countries, including Brazil and it plays a role in preventing, protecting, promoting, and treating individuals and communities. Brazil, like other countries, has faced the SARS-CoV-2 pandemic. As Brazil has a universal and decentralized health system, in which PHC has been the model of health re-organizing the health system; here we reflected the importance of strengthening PHC in Brazil in the times of coronavirus disease 2019 pandemic.


Subject(s)
Betacoronavirus , Coronavirus Infections/prevention & control , Health Services Needs and Demand/standards , National Health Programs/standards , Pandemics/prevention & control , Pneumonia, Viral/prevention & control , Primary Health Care/standards , Brazil , COVID-19 , Health Services Needs and Demand/organization & administration , Hospitalization/statistics & numerical data , Humans , National Health Programs/organization & administration , Primary Health Care/organization & administration , SARS-CoV-2
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